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Article

Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.

Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 2009

Kruse Elizabeth A, Loughran Stephen J, Baldwin Tracey M, Josefsson Emma C, Ellis Sarah, Watson Dennis K, Nurden Paquita, Metcalf Donald, Hilton Douglas J, Alexander Warren S, Kile Benjamin T

Abstract excerpt

Fli-1 and Erg are closely related members of the Ets family of transcription factors. Both genes are translocated in human cancers, including Ewing's sarcoma, leukemia, and in the case of Erg, more than half of all prostate cancers. Although evidence from mice and humans suggests that Fli-1 is re...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19666492
DOI: 10.1073/pnas.0906556106
PMCID: PMC2728977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19666492-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.PMID 19666492Read ↗

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