Article
Changing Val-76 towards Kir channels drastically influences the folding and gating properties of the bacterial potassium channel KcsA.
Biophysical chemistry - 1 Oct 2009
Raja Mobeen, Vales Elisabeth
Abstract excerpt
All K(+)-channels are stabilized by K(+)-ions in the selectivity filter. However, they differ from each other with regard to their selectivity filter. In this study, we changed specific residue Val-76 in the selectivity filter of KcsA to its counterpart Ile in inwardly rectifying K(+)-channels (K...
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