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Article

A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.

Journal of molecular biology - 7 May 2004

Zhou Ming, MacKinnon Roderick

Abstract excerpt

The selectivity filter of K(+) channels is comprised of a linear queue of four equal-spaced ion-binding sites spanning a distance of 12A. Each site is formed of eight oxygen atoms from the protein. The first three sites, numbered 1-3 from the extracellular side, are made of exclusively main-chain carbonyl oxygen atoms. The fourth site, closest to the intracellular side, is made of four main-chain carbonyl oxygen...

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Identifiers

PMID: 15099749
DOI: 10.1016/j.jmb.2004.03.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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