Article
A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease.
American journal of human genetics - 1 Aug 2009
Ko Dennis C, Shukla Kajal P, Fong Christine, Wasnick Michael, Brittnacher Mitchell J, Wurfel Mark M, Holden Tarah D, O'Keefe Grant E, Van Yserloo Brian, Akey Joshua M, Miller Samuel I
Abstract excerpt
Recent progress in cataloguing common genetic variation has made possible genome-wide studies that are beginning to elucidate the causes and consequences of our genetic differences. Approaches that provide a mechanistic understanding of how genetic variants function to alter disease susceptibilit...
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