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Article

Natural genetic variation in Drosophila melanogaster reveals genes associated with Coxiella burnetii infection.

Genetics - 31 Mar 2021

Guzman Rosa M, Howard Zachary P, Liu Ziying, Oliveira Ryan D, Massa Alisha T, Omsland Anders, White Stephen N, Goodman Alan G

Abstract excerpt

The gram-negative bacterium Coxiella burnetii is the causative agent of Query (Q) fever in humans and coxiellosis in livestock. Host genetics are associated with C. burnetii pathogenesis both in humans and animals; however, it remains unknown if specific genes are associated with severity of infection. We employed the Drosophila Genetics Reference Panel to perform a genome-wide association study to identify host...

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Identifiers

PMID: 33789347
DOI: 10.1093/genetics/iyab005
PMCID: PMC8045698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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