Article
YidC is required for the assembly of the MscL homopentameric pore.
The FEBS journal - 1 Sept 2009
Pop Ovidiu I, Soprova Zora, Koningstein Gregory, Scheffers Dirk-Jan, van Ulsen Peter, Wickström David, de Gier Jan-Willem, Luirink Joen
Abstract excerpt
The mechanosensitive channel with large conductance (MscL) of Escherichia coli is formed by a homopentameric assembly of MscL proteins. Here, we describe MscL biogenesis as determined using in vivo approaches. Evidence is presented that MscL is targeted to the inner membrane via the signal recogn...
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