Article
YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery.
The Journal of biological chemistry - 27 Sept 2013
Zhu Lu, Kaback H Ronald, Dalbey Ross E
Abstract excerpt
To understand how YidC and SecYEG function together in membrane protein topogenesis, insertion and folding of the lactose permease of Escherichia coli (LacY), a 12-transmembrane helix protein LacY that catalyzes symport of a galactoside and an H(+), was studied. Although both the SecYEG machinery and signal recognition particle are required for insertion of LacY into the membrane, YidC is not required for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
