Article
MscL of Bacillus subtilis prevents selective release of cytoplasmic proteins in a hypotonic environment.
Proteomics - 1 Feb 2009
Kouwen Thijs R H M, Antelmann Haike, van der Ploeg René, Denham Emma L, Hecker Michael, van Dijl Jan Maarten
Abstract excerpt
Bacillus subtilis serves as an excellent model to study protein secretion at a proteomic scale. Most of the extracellular proteins are exported from the cytoplasm via the secretory (Sec) pathway. Despite extensive studies, the secretion mechanisms of about 25% of the extracellular proteins are unknown. This suggests that B. subtilis makes use of alternative mechanisms to release proteins into its environment. In...
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