Article
Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients.
International journal of cancer - 1 Feb 2010
Lu Janice, Fan Tina, Zhao Qiang, Zeng Wei, Zaslavsky Eva, Chen John J, Frohman Michael A, Golightly Marc G, Madajewicz Stefan, Chen Wen-Tien
Abstract excerpt
Recent research advances show that tumor cell intravasation (entry into the circulation) and metastasis occur very early in breast cancer progression. Clinical studies also illustrate the potential importance of detection of circulating tumor cells (CTCs) in outcomes of patients with metastatic breast cancer. Whether these cells exhibit the invasiveness and express tumor stem or progenitor markers, hallmark of...
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