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Molecular Biomarker Analyses Using Circulating Tumor Cells

8 Sept 2010

Abstract excerpt

BACKGROUND: Evaluation of cancer biomarkers from blood could significantly enable biomarker assessment by providing a relatively non-invasive source of representative tumor material. Circulating Tumor Cells (CTCs) isolated from blood of metastatic cancer patients hold significant promise in this regard. METHODOLOGY/PRINCIPAL FINDINGS: Using spiked tumor-cells we evaluated CTC capture on different CTC technology...

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PMID: 20838621
DOI: 10.1371/journal.pone.0012517

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