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Article

Bruton’s Tyrosine Kinase Targeting in Multiple Myeloma

27 May 2021

Abstract excerpt

Multiple myeloma (MM), a clonal plasma cell disorder, disrupts the bones' hematopoiesis and microenvironment homeostasis and ability to mediate an immune response against malignant clones. Despite prominent survival improvement with newer treatment modalities since the 2000s, MM is still considered a non-curable disease. Patients experience disease recurrence episodes with clonal evolution, and with each relapse...

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PMID: 34071917
DOI: 10.3390/ijms22115707

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