Article

Identification of biomarkers and candidate regulators for multiple myeloma under the knockout of AURKA

2021-03-22

Abstract excerpt

Multiple myeloma (MM) is a plasma cell malignancy that is characterized by the overabundance of monoclonal paraprotein. Aurora kinase A (AURKA) was upregulated in patients with high-risk MM. AURKA inhibitors were used to inhibit MM cell proliferation by inducing cell apoptosis and injury. In our study, we aim to identify biological processes and pathways of MM cells under the knockout of AURKA (AURKA KO) by using...

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Literature Corpus work: 6bc70d11-0391-58be-8c04-ddf9865c690f
DOI: 10.1101/2021.03.21.436324

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