Article
mec-15 encodes an F-box protein required for touch receptor neuron mechanosensation, synapse formation and development.
Genetics - 1 Oct 2009
Bounoutas Alexander, Zheng Qun, Nonet Michael L, Chalfie Martin
Abstract excerpt
Selective protein degradation is a key regulator of neuronal development and synaptogenesis. Complexes that target proteins for degradation often contain F-box proteins. Here we characterize MEC-15, an F-box protein with WD repeats, which is required for the development and function of Caenorhabd...
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