Genes regulating touch cell development in Caenorhabditis elegans.

doi:10.1093/genetics/158.1.197

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Article

Genes regulating touch cell development in Caenorhabditis elegans.

Genetics - 1 May 2001

Du H, Chalfie M

Abstract excerpt

To identify genes regulating the development of the six touch receptor neurons, we screened the F(2) progeny of mutated animals expressing an integrated mec-2::gfp transgene that is expressed mainly in these touch cells. From 2638 mutated haploid genomes, we obtained 11 mutations representing 11 genes that affected the production, migration, or outgrowth of the touch cells. Eight of these mutations were in known...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis elegans
Cell Differentiation
Cell Lineage
DNA Primers
Embryo, Nonmammalian
Genes, Homeobox
Humans
Molecular Sequence Data
Mutation
Reverse Transcriptase Polymerase Chain Reaction
Sequence Homology, Amino Acid

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Identifiers

PMID: 11333230
DOI: 10.1093/genetics/158.1.197
PMCID: PMC1461620

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