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Article

Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology.

Addiction biology - 1 Sept 2009

Benyamina Amine, Saffroy Raphaël, Blecha Lisa, Pham Patrick, Karila Laurent, Debuire Brigitte, Lemoine Antoinette, Reynaud Michel

Abstract excerpt

Prior studies have associated 677C-T Methylenetetrahydrofolate reductase (MTHFR) gene polymorphism with decreased enzymatic activity and modified homocysteine regulation. This study determines and compares MTHFR 677C-T distribution and examines its consequences on homocysteine metabolism and alcohol dependence in alcoholic patients classified according to the Babor and Lesch typologies. MTHFR TT genotype was more...

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Source

Identifiers

PMID: 19650814
DOI: 10.1111/j.1369-1600.2009.00169.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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