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Article

Different allele-distribution of mthfr 677 C -> T and mthfr -393 C -> a in patients classified according to subtypes of Lesch's typology.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Bönsch Dominikus, Bayerlein Kristina, Reulbach Udo, Fiszer Roland, Hillemacher Thomas, Sperling Wolfgang, Kornhuber Johannes, Bleich Stefan

Abstract excerpt

AIMS: The typology by Lesch distinguishes between four subtypes: type 1 (model of allergy), type 2 (model of anxiety or conflict), type 3 (alcohol as an antidepressant), and type 4 (alcohol as adaptation). Taking into account that alcohol dependence is associated with elevated homocysteine levels, this study was undertaken to investigate different MTHFR (methylenetetrahydrofolate reductase) genotypes related to...

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Identifiers

PMID: 16627623
DOI: 10.1093/alcalc/agl024

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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