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Article

Genetics of Lesch's typology of alcoholism.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Feb 2008

Samochowiec Jerzy, Kucharska-Mazur Jolanta, Grzywacz Anna, Pelka-Wysiecka Justyna, Mak Monika, Samochowiec Agnieszka, Bienkowski Przemyslaw

Abstract excerpt

It is widely accepted that dopamine and serotonin (5-HT) neurotransmission can be critically involved in the development of alcohol abuse and alcohol dependence. Lesch's typology of alcoholism has been gaining increasing popularity as it qualitatively differentiates patients into different treatment response subgroups. The aim of the present study was to evaluate a possible genetic background of Lesch's typology...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17928119
DOI: 10.1016/j.pnpbp.2007.09.013

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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