Article

DNA Methylation change in genes involved in Alcohol metabolism (ALDH2) and One-carbon metabolism (MTHFR) pathways among people with Alcohol Use Disorder

2025-11-13

Abstract excerpt

<title>Abstract</title> <p> Background: Alcohol Use Disorder (AUD) is a significant public health issue influenced by genetic and environmental factors. Genetic loci linked to age of initiation, response to alcohol, and withdrawal complications.Alcohol inhibits methionine synthase (MS), disrupting the conversion of homocysteine to methionine and altering levels of S-adenosyl methionine (SAM) and S-adenosylhomocy...

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Literature Corpus work: e7df8de9-0c83-5be2-9b84-4069b148b1fe
DOI: 10.21203/rs.3.rs-8049845/v1

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