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Article

The circadian gene NPAS2 is a novel prognostic biomarker for breast cancer.

Breast cancer research and treatment - 1 Apr 2010

Yi Chunhui, Mu Lina, de la Longrais Irene A Rigault, Sochirca Olga, Arisio Riccardo, Yu Herbert, Hoffman Aaron E, Zhu Yong, Katsaro Dionyssios

Abstract excerpt

Mounting evidence suggests that neuronal PAS domain protein 2 (NPAS2) and other circadian genes are involved in tumorigenesis and tumor growth, possibly through their control of cancer-related biologic pathways. A missense polymorphism in NPAS2 (Ala394Thr) has been shown to be associated with risk of human tumors including breast cancer. The current study further examined the prognostic significance of NPAS2 in...

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Source

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Identifiers

PMID: 19649706
DOI: 10.1007/s10549-009-0484-0
PMCID: PMC3108061

Genes

NPAS2
AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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