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Article

Recently discovered T cell subsets cannot keep their commitments.

Journal of the American Society of Nephrology : JASN - 1 Aug 2009

Strom Terry B, Koulmanda Maria

Abstract excerpt

After activation by antigen/MHC (signal 1) and CD28-dependent co-stimulation (signal 2), resting CD4(+) T cells commit to one of a variety of functionally and molecularly defined phenotypes. Two long established CD4 phenotypes, Th1 and Th2 cells, have been regarded as terminally differentiated formats. Recently, two additional phenotypes, tissue-protective regulatory (Tregs) and tissue-destructive Th17 T cells,...

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Identifiers

PMID: 19648467
DOI: 10.1681/ASN.2008101027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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