Article
Developmental control of inositol phosphate biosynthesis is altered in the brain of both curly and phenotypically normal straight tail mutant mice.
Birth defects research. Part A, Clinical and molecular teratology - 1 Oct 2009
Alebous Hana Dawood Ali, Cartee Robert, Vaccari David, Wright Oneil A, Ahmed Altan, Hood Ronald D, Johnson Margaret Dean
Abstract excerpt
BACKGROUND: Altered levels of inositol phosphate in the central nervous system (CNS) are hypothesized to produce distorted brain signaling and lead to numerous neurologic maladies. Little is known of mechanisms controlling the complex metabolic flux of inositol phosphate. Less is known of controls that regulate inositol-phosphate biosynthesis in the mammalian brain. The expression of 1L-myo-inositol-1 phosphate...
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