Article
Phenotype of the neural tube defect mouse model bent tail is not sensitive to maternal folinic acid, myo-inositol, or zinc supplementation.
Birth defects research. Part A, Clinical and molecular teratology - 1 Dec 2003
Franke Barbara, Klootwijk Riko, Lemmers Bianca, de Kovel Carolien G F, Steegers-Theunissen Regine P M, Mariman Edwin C M
Abstract excerpt
BACKGROUND: Bent tail is a mouse model for X-linked neural tube defects (NTDs) that is characterized by the presence of exencephaly, a delayed posterior neuropore closure, and a tail phenotype. In addition, Bent tail shows laterality defects and increased prenatal mortality. The congenital malformations of this mouse are caused by a submicroscopic deletion that completely encompasses the gene coding for the zinc...
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