Article
Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice.
BMC neuroscience - 5 Mar 2007
Li Yan, Semaan Sheila J, Schlamp Cassandra L, Nickells Robert W
Abstract excerpt
BACKGROUND: Several neurodegenerative diseases are influenced by complex genetics that affect an individual's susceptibility, disease severity, and rate of progression. One such disease is glaucoma, a chronic neurodegenerative condition of the eye that targets and stimulates apoptosis of CNS neurons called retinal ganglion cells. Since ganglion cell death is intrinsic, it is reasonable that the genes that control...
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