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Article

TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2009

Chassin Cécilia, Picardeau Mathieu, Goujon Jean-Michel, Bourhy Pascale, Quellard Nathalie, Darche Sylvie, Badell Edgar, d'Andon Martine Fanton, Winter Nathalie, Lacroix-Lamandé Sonia, Buzoni-Gatel Dominique, Vandewalle Alain, Werts Catherine

Abstract excerpt

Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira interrogans that are transmitted by asymptomatic infected rodents. Leptospiral lipoproteins and LPS have been shown to stimulate murine cells via TLRs 2 and 4. Host defense mechanisms remain obscure, although TLR4 has been sho...

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Source

Identifiers

PMID: 19635914
DOI: 10.4049/jimmunol.0900506

Genes

TLR4
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19635914-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans.PMID 19635914Read ↗

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