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Responses of Murine and Human Macrophages to Leptospiral Infection: A Study Using Comparative Array Analysis

10 Oct 2013

Abstract excerpt

Leptospirosis is a re-emerging tropical infectious disease caused by pathogenic Leptospira spp. The different host innate immune responses are partially related to the different severities of leptospirosis. In this study, we employed transcriptomics and cytokine arrays to comparatively calculate the responses of murine peritoneal macrophages (MPMs) and human peripheral blood monocytes (HBMs) to leptospiral...

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PMID: 24130911
DOI: 10.1371/journal.pntd.0002477

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