Article
The twin spot generator for differential Drosophila lineage analysis.
Nature methods - 1 Aug 2009
Griffin Ruth, Sustar Anne, Bonvin Marianne, Binari Richard, del Valle Rodriguez Alberto, Hohl Amber M, Bateman Jack R, Villalta Christians, Heffern Elleard, Grunwald Didier, Bakal Chris, Desplan Claude, Schubiger Gerold, Wu C-ting, Perrimon Norbert
Abstract excerpt
In Drosophila melanogaster, widely used mitotic recombination-based strategies generate mosaic flies with positive readout for only one daughter cell after division. To differentially label both daughter cells, we developed the twin spot generator (TSG) technique, which through mitotic recombinat...
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