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Article

Versatile CRISPR/Cas9-mediated mosaic analysis by gRNA-induced crossing-over for unmodified genomes.

PLoS biology - 1 Jan 2021

Allen Sarah E, Koreman Gabriel T, Sarkar Ankita, Wang Bei, Wolfner Mariana F, Han Chun

Abstract excerpt

Mosaic animals have provided the platform for many fundamental discoveries in developmental biology, cell biology, and other fields. Techniques to produce mosaic animals by mitotic recombination have been extensively developed in Drosophila melanogaster but are less common for other laboratory organisms. Here, we report mosaic analysis by gRNA-induced crossing-over (MAGIC), a new technique for generating mosaic...

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Identifiers

PMID: 33444322
DOI: 10.1371/journal.pbio.3001061
PMCID: PMC7837743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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