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Article

Interleukin-1 beta -511C/T genetic polymorphism is associated with age of onset of geriatric depression.

Neuromolecular medicine - 1 Jan 2009

Hwang Jen-Ping, Tsai Shih-Jen, Hong Chen-Jee, Yang Chen-Hong, Hsu Cheng-Dien, Liou Ying-Jay

Abstract excerpt

The pro-inflammatory cytokine interleukin-1 beta has been implicated in the pathogenesis of major depressive disorder and in cognitive function decline in the elderly. This study tests the hypothesis that a biallelic functional polymorphism in the promoter region of the interleukin-1 beta gene (IL1B -511C/T) affects vulnerability to geriatric depression and its manifestations, including age of onset, depression...

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Source

Identifiers

PMID: 19629761
DOI: 10.1007/s12017-009-8078-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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