Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preerythrocytic, live-attenuated <i>Plasmodium falciparum</i> vaccine candidates by design

22 Jul 2009

Abstract excerpt

Falciparum malaria is initiated when Anopheles mosquitoes transmit the Plasmodium sporozoite stage during a blood meal. Irradiated sporozoites confer sterile protection against subsequent malaria infection in animal models and humans. This level of protection is unmatched by current recombinant malaria vaccines. However, the live-attenuated vaccine approach faces formidable obstacles, including development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Parasites and Host Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19625622
DOI: 10.1073/pnas.0906387106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preerythrocytic, live-attenuated <i>Plasmodium falciparum</i> vaccine candidates by designPMID 19625622Read ↗

A Next-generation Genetically Attenuated Plasmodium falciparum Parasite Created by Triple Gene DeletionSemantic proximity Read ↗

A replication-competent late liver stage–attenuated human malaria parasiteSemantic proximity Read ↗

Protracted Sterile Protection with<i>Plasmodium yoelii</i>Pre‐erythrocytic Genetically Attenuated Parasite Malaria Vaccines Is Independent of Significant Liver‐Stage Persistence and Is Mediated by CD8<sup>+</sup>T CellsSemantic proximity Read ↗

Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liverSemantic proximity Read ↗

A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletionSemantic proximity Read ↗

Designer Parasites: Genetically Engineered Plasmodium as Vaccines To Prevent Malaria InfectionSemantic proximity Read ↗

A conserved <i>Plasmodium</i> protein that localizes to liver stage nuclei is critical for late liver stage developmentSemantic proximity Read ↗

Genetically engineered, attenuated whole-cell vaccine approaches for malariaSemantic proximity Read ↗

Protective efficacy and safety of liver stage attenuated malaria parasitesSemantic proximity Read ↗

<i>Plasmodium knowlesi</i>Provides a Rapid In Vitro and In Vivo Transfection System That Enables Double-Crossover Gene Knockout StudiesSemantic proximity Read ↗

A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life CycleSemantic proximity Read ↗

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoitesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.