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<i>Plasmodium knowlesi</i>Provides a Rapid In Vitro and In Vivo Transfection System That Enables Double-Crossover Gene Knockout Studies

1 Feb 2002

Abstract excerpt

Transfection technology for malaria parasites provides a valuable tool for analyzing gene function and correlating genotype with phenotype. Transfection models are even more valuable when appropriate animal models are available in addition to complete in vitro systems to be able to fully analyze parasite-host interactions. Here we describe the development of such a model by using the nonhuman primate malaria...

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PMID: 11796595
DOI: 10.1128/iai.70.2.655-660.2002

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