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Article

Sugar-binding activity of the MRH domain in the ER alpha-glucosidase II beta subunit is important for efficient glucose trimming.

Glycobiology - 1 Oct 2009

Hu Dan, Kamiya Yukiko, Totani Kiichiro, Kamiya Daiki, Kawasaki Norihito, Yamaguchi Daisuke, Matsuo Ichiro, Matsumoto Naoki, Ito Yukishige, Kato Koichi, Yamamoto Kazuo

Abstract excerpt

Glucosidase II (GII) is a glycan-processing enzyme that trims two alpha1,3-linked glucose residues from N-glycan on newly synthesized glycoproteins. Trimming of the first alpha1,3-linked glucose from Glc(2)Man(9)GlcNAc(2) (G2M9) is important for a glycoprotein to interact with calnexin/calreticul...

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PMID: 19625484
DOI: 10.1093/glycob/cwp104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19625484-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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