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Article

Effects of PCSK9 variants on common carotid artery intima media thickness and relation to ApoE alleles.

Atherosclerosis - 1 Jan 2010

Norata Giuseppe Danilo, Garlaschelli Katia, Grigore Liliana, Raselli Sara, Tramontana Simona, Meneghetti Fiorella, Artali Roberto, Noto Davide, Cefalù Angelo Baldassare, Buccianti Gherardo, Averna Maurizio, Catapano Alberico Luigi

Abstract excerpt

BACKGROUND: PCSK9 plays a key role in plasma cholesterol metabolism by modulating the expression of LDL receptors. OBJECTIVE AND METHODS: In this study we investigated the effects of two common polymorphism of the PCSK9 gene (E670G and I474V) on the intima media thickness of the common carotid artery and the possible relation with polymorphisms of apolipoprotein E in 1541 middle aged subjects selected from the...

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Source

Identifiers

PMID: 19619878
DOI: 10.1016/j.atherosclerosis.2009.06.023

Genes

PCSK9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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