Effect of E670G Polymorphism in PCSK9 Gene on the Risk and Severity of Coronary Heart Disease and Ischemic Stroke in a Tunisian Cohort.

doi:10.1007/s12031-014-0238-2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Effect of E670G Polymorphism in PCSK9 Gene on the Risk and Severity of Coronary Heart Disease and Ischemic Stroke in a Tunisian Cohort.

Journal of molecular neuroscience : MN - 1 Jun 2014

Slimani Afef, Harira Yahia, Trabelsi Imen, Jomaa Walid, Maatouk Faouzi, Hamda Khaldoun Ben, Slimane Mohamed Naceur

Abstract excerpt

The association of E670G (rs505151) polymorphism in PCSK9 gene with an increased risk of coronary artery disease (CAD) and ischemic stroke (IS) was reported in previous studies. We investigated the effect of the E670G (rs505151) on the risk of CAD and IS in a Tunisian cohort. Genotyping of the PCSK9 E670G was performed using polymerase chain reaction (PCR)-based restriction fragment length polymorphism (RFLP) and...

Topics

Join the communities discussing this publication.

Brain Ischemia
Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Coronary Artery Disease

Proprotein Convertase 9

Proprotein Convertases

Serine Endopeptidases

Stroke

Tunisia

Source

Open in PubMed

Identifiers

PMID: 24599757
DOI: 10.1007/s12031-014-0238-2

Genes

CAD
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of E670G Polymorphism in PCSK9 Gene on the Risk and Severity of Coronary Heart Disease and Ischemic Stroke in a Tunisian Cohort.PMID 24599757Read ↗

PCSK9 E670G polymorphism increases risk of coronary artery disease in a Chinese Han population.Semantic proximity Read ↗

PCSK9 E670G (rs505151) Variant and Coronary Artery Disease Risk Among Diabetics.Semantic proximity Read ↗

PCSK9 polymorphism in a Tunisian cohort: identification of a new allele, L8, and association of allele L10 with reduced coronary heart disease risk.Semantic proximity Read ↗

[Influence of PCSK9 gene E670G polymorphism on the risk of atherosclerotic coronary heart disease and plasma lipid level].Semantic proximity Read ↗

Polymorphisms of rs2483205 and rs562556 in the PCSK9 gene are associated with coronary artery disease and cardiovascular risk factors.Semantic proximity Read ↗

Association of APOB (rs515135) and PCSK9 (rs505151) gene polymorphisms with CAD in the Indian population.Semantic proximity Read ↗

The associations between proprotein convertase subtilisin/kexin type 9 E670G polymorphism and the risk of coronary artery disease and serum lipid levels: a meta-analysis.Semantic proximity Read ↗

Proprotein Convertase Subtilisin/Kexin Type 9 Gene Polymorphism (PCSK9) in Coronary Heart DiseasesSemantic proximity Read ↗

Polymorphisms of rs2483205 and rs562556 in Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Gene are Associated With Coronary Artery DiseaseSemantic proximity Read ↗

The Impact of PCSK9 Gene Polymorphisms on Ischemic Stroke: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

<i>PCSK9</i>genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populationsSemantic proximity Read ↗

Correlation of PCSK9 gene polymorphism with cerebral ischemic stroke in Xinjiang Han and Uygur populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.