Article
Candidate gene analysis of femoral neck trabecular and cortical volumetric bone mineral density in older men.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2010
Yerges Laura M, Klei Lambertus, Cauley Jane A, Roeder Kathryn, Kammerer Candace M, Ensrud Kristine E, Nestlerode Cara S, Lewis Cora, Lang Thomas F, Barrett-Connor Elizabeth, Moffett Susan P, Hoffman Andrew R, Ferrell Robert E, Orwoll Eric S, Zmuda Joseph M
Abstract excerpt
In contrast to conventional dual-energy X-ray absorptiometry, quantitative computed tomography separately measures trabecular and cortical volumetric bone mineral density (vBMD). Little is known about the genetic variants associated with trabecular and cortical vBMD in humans, although both may be important for determining bone strength and osteoporotic risk. In the current analysis, we tested the hypothesis that...
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