Article
Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Apr 2011
Zmuda J M, Yerges-Armstrong L M, Moffett S P, Klei L, Kammerer C M, Roeder K, Cauley J A, Kuipers A, Ensrud K E, Nestlerode C S, Hoffman A R, Lewis C E, Lang T F, Barrett-Connor E, Ferrell R E, Orwoll E S
Abstract excerpt
We investigated 383 bone candidate genes for associations between single nucleotide polymorphisms and vertebral trabecular volumetric bone mineral density (vBMD) and cross-sectional area (CSA) in 2,018 Caucasian men aged ≥ 65 years. SNPs in TGFBR3, SOST, KL, CALCR, LEP, CSF1R, PTN, GNRH2, FGFR2, and MEPE were associated with vBMD and SNPs in CYP11B1, DVL2, DLX5, WNT4, and PAX7 were associated with CSA in...
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