Article
Effect of butyrylcholinesterase genotype on the response to rivastigmine or donepezil in younger patients with Alzheimer's disease.
Pharmacogenetics and genomics - 1 Nov 2006
Blesa Rafael, Bullock Roger, He Yunsheng, Bergman Howard, Gambina Giuseppe, Meyer Joanne, Rapatz Günter, Nagel Jennifer, Lane Roger
Abstract excerpt
A randomized double-blind trial evaluated the efficacy and tolerability of rivastigmine, an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), and donepezil, an AChE-selective inhibitor, in patients with Alzheimer's disease over a 2-year period. A retrospective analysis s...
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