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Lung-specific inactivation of CCAAT/enhancer binding protein α causes a pathological pattern characteristic of COPD

16 Jul 2009

Abstract excerpt

The link between respiratory complications in prematurely born infants and susceptibility for developing chronic obstructive pulmonary disease (COPD) is receiving increasing attention. We have previously found that CCAAT/enhancer binding protein (C/EBP) activity in airway epithelial cells of COPD patients is decreased compared to healthy smokers, suggesting a previously unknown role for C/EBPs in COPD...

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PMID: 19608583
DOI: 10.1183/09031936.00185008

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