Article
The role of C/EBPbeta in mammary gland development and breast cancer.
Journal of mammary gland biology and neoplasia - 1 Apr 2003
Grimm Sandra L, Rosen Jeffrey M
Abstract excerpt
The CCAAT/enhancer binding protein (C/EBP) family of bZIP transcription factors control the proliferation and differentiation of a variety of tissues. While C/EBPalpha and -delta are also expressed in the mammary gland, the multiple protein isoforms of C/EBPbeta appear to play a critical role in mammary gland development and breast cancer. Targeted deletion of all the C/EBPbeta isoforms results in a severe...
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