Article
Association of TWIST1 gene polymorphisms with bone mineral density in postmenopausal women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 May 2010
Hwang J-Y, Kim S-Y, Lee S H, Kim G S, Go M J, Kim S E, Kim H-C, Shin H-D, Park B L, Kim T-H, Hong J M, Park E K, Kim H-L, Lee J-Y, Koh J-M
Abstract excerpt
UNLABELLED: A novel polymorphism (+1871A>G) in the 3' flanking region and haplotypes were significantly associated with reduced osteoporosis risk and enhanced bone mineral density (BMD). These results suggest that TWIST1 may be a useful genetic marker for osteoporosis. Our results provide preliminary evidence supporting an association of TWIST1 with osteoporosis in postmenopausal women. INTRODUCTION: TWIST1, a...
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