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Article

Polymorphisms in the transforming growth factor beta 1 gene and osteoporosis.

Bone - 1 Mar 2003

Langdahl Bente Lomholt, Carstens Mette, Stenkjaer Liselotte, Eriksen Erik Fink

Abstract excerpt

Transforming growth factor (TGF)-beta1 is the most abundant growth factor in human bone. It is produced by osteoblasts and inhibits osteoclast proliferation and activity and stimulates proliferation and differentiation of preosteoblasts. Several polymorphisms have been described in the TGF-beta1 gene. Previously, we and others have found associations between some of these polymorphisms and bone mass. We therefore...

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PMID: 12667558
DOI: 10.1016/s8756-3282(02)00971-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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