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Article

MTHFR C677T genotype frequency in patients of Middle Eastern descent as determined by real-time PCR and melting curve analysis.

Genetic testing and molecular biomarkers - 1 Aug 2009

Haghighatgoo Arman, Valles-Ayoub Yadira, Saechao Chai, Esfandiarifard Saghi, Martinez Sarah L, Pietruszka Marvin, Darvish Daniel

Abstract excerpt

The 5,10-methylenetetrahydrofolate reductase gene (MTHFR) 677C>T polymorphism produces an elevation in plasma homocysteine concentrations when present in the homozygous state. Increased homocysteine levels have been associated with a greater risk for vascular diseases, including cardiovascular disease and ischemic stroke. In this study, we genotyped 42 nucleic acid samples for the C677T allele from our database...

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Identifiers

PMID: 19594372
DOI: 10.1089/gtmb.2009.0008

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MTHFR C677T genotype frequency in patients of Middle Eastern descent as determined by real-time PCR and melting curve analysis.PMID 19594372Read ↗

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