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Article

An expanding job description for Blimp-1/PRDM1.

Current opinion in genetics & development - 1 Aug 2009

Bikoff Elizabeth K, Morgan Marc A, Robertson Elizabeth J

Abstract excerpt

The master transcriptional regulator Blimp-1/PRDM1 contains an N-terminal PR/SET domain and five C2H2 zinc fingers located near its C-terminus that mediate DNA binding, nuclear import and recruitment of histone modifying enzymes. These activities account for its ability to control cell-fate decisions in the embryo and govern tissue homeostasis in multiple cell types in the adult organism. New experiments...

Read the complete abstract on PubMed

Topics

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Share to Cell Lineage
Share to Gene Expression Regulation, Developmental
Share to Histone Deacetylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Nuclear Proteins

Share to Positive Regulatory Domain I-Binding Factor 1

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Source

Identifiers

PMID: 19592232
DOI: 10.1016/j.gde.2009.05.005

Genes

PRDM1
SET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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