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Article

NAD(P)H: Quinone oxidoreductase 1, glutathione S-transferase M1, environmental tobacco smoke exposure, and childhood asthma.

Mutation research - 1 Aug 2009

Li Yu-Fen, Tseng Pei-Jung, Lin Che-Chen, Hung Chiao-Ling, Lin Sheng-Che, Su Wan-Cing, Huang Yi-Ling, Sung Fung-Chang, Tai Chien-Kuo

Abstract excerpt

Environmental tobacco smoke (ETS) exposure might increase the risk for childhood asthma, and we hypothesized the effect may be modified by the phase II genes NAD(P)H: quinone oxidoreductase 1 (NQO1) and glutathione S-transferase (GST) M1. To investigate the genetic and environmental associations with asthma, GSTM1 and NQO1 functional polymorphisms and ETS were analyzed in a two-staged cross-sectional study among...

Topics

Asthma
Child
Female
Genetic Predisposition to Disease
Glutathione Transferase
Humans
Male
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Genetic
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tobacco Smoke Pollution

Source

Identifiers

PMID: 19591959
DOI: 10.1016/j.mrgentox.2009.06.008

Genes

NQO1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19591959-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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