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Article

Nicotinamide adenine dinucleotide (phosphate) reduced:quinone oxidoreductase and glutathione S-transferase M1 polymorphisms and childhood asthma.

American journal of respiratory and critical care medicine - 15 Nov 2003

David Gloria L, Romieu Isabelle, Sienra-Monge Juan Jose, Collins William J, Ramirez-Aguilar Matiana, del Rio-Navarro Blanca Estela, Reyes-Ruiz Norma Isabel, Morris Richard W, Marzec Jacqueline M, London Stephanie J

Abstract excerpt

Nicotinamide adenine dinucleotide (phosphate) reduced:quinone oxidoreductase (NQO1) and glutathione S-transferase (GST) M1 are phase II enzymes important in response to oxidative stress, such as occurs during exposure to ozone. We examined the relationship between functionally significant polymorphisms in NQO1 (Pro187Ser) and GSTM1 (homozygous deletion) and asthma risk in children with high lifetime exposure to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12969868
DOI: 10.1164/rccm.200305-684OC

Genes

NQO1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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