Article
The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition.
Developmental biology - 15 Sept 2009
Denaxa Myrto, Sharpe Paul T, Pachnis Vassilis
Abstract excerpt
Genes encoding LIM homeodomain transcription factors are implicated in cell type specification and differentiation during embryogenesis. Two closely related members of this family, Lhx6 and Lhx7, are expressed in the ectomesenchyme of the maxillary and mandibular processes and have been suggested to control patterning of the first branchial arch (BA1) and odontogenesis. However, mice homozygous for single...
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