Article

Hedgehog signalling regulates patterning of the murine and human dentitions through Gas1 co-receptor function

2020-11-07

Abstract excerpt

<h4>ABSTRACT</h4> The mammalian dentition exhibits wide numerical and morphological variation between different species. The regulation of dental pattern is achieved through complex reiterative molecular signalling interactions that occur through multiple stages of tooth development. We show that mice with loss-of-function in the Hedgehog co-receptor Gas1 have variation in size, morphology and number of teeth wit...

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Literature Corpus work: c3b2863b-c393-518c-bb8b-37efff212ce1
DOI: 10.1101/2020.11.06.371476

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