Article
Divergence of ape and human monoamine oxidase A gene promoters: comparative analysis of polymorphisms, tandem repeat structures and transcriptional activities on reporter gene expression.
Neuroscience letters - 25 Sept 2006
Inoue-Murayama Miho, Mishima Noriko, Hayasaka Ikuo, Ito Shin'ichi, Murayama Yuichi
Abstract excerpt
A variable number of tandem repeats (VNTR) polymorphism based on a 30-bp unit have been reported in the promoter region of the human monoamine oxidase A gene (MAOA). Human VNTRs have been shown to affect transcriptional activity, and some reports suggest that VNTR polymorphisms are associated with psychoneurological disorders. VNTR polymorphism has also been reported in the ape MAOA promoter but the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.