Article
Differential contribution of CDKAL1 variants to psoriasis, Crohn's disease and type II diabetes.
Genes and immunity - 1 Oct 2009
Quaranta M, Burden A D, Griffiths C E M, Worthington J, Barker J N, Trembath R C, Capon F
Abstract excerpt
Psoriasis is an immune-mediated skin disorder, which is inherited as a complex trait. Genome-wide linkage and association studies have identified a major disease susceptibility locus on chromosome 6p21, as well as a number of genetic determinants of smaller effect. Our group has also documented a...
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