Article
Epigenome-Wide Association Analysis Identified Nine Skin DNA Methylation Loci for Psoriasis.
The Journal of investigative dermatology - 1 Apr 2016
Zhou Fusheng, Wang Wenjun, Shen Changbing, Li Hui, Zuo Xianbo, Zheng Xiaodong, Yue Min, Zhang Cuicui, Yu Liang, Chen Mengyun, Zhu Caihong, Yin Xianyong, Tang Mingjun, Li Yongjiang, Chen Gang, Wang Zaixing, Liu Shengxiu, Zhou Yi, Zhang Fengyu, Zhang Weijia, Li Caihua, Yang Sen, Sun Liangdan, Zhang Xuejun
Abstract excerpt
Psoriasis is a chronic hyperproliferative and inflammatory skin disease caused by the interplay of genetic and environmental factors. DNA methylation has been linked to psoriasis, but the manner in which this process contributes to the disease is not fully understood. In this study, we carried out a three-stage epigenome-wide association study to identify disease-associated differentially methylated sites using a...
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