FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.

doi:10.1371/journal.pone.0002958

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Article

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.

PloS one - 13 Aug 2008

Kring Sofia I I, Holst Claus, Zimmermann Esther, Jess Tine, Berentzen Tina, Toubro Søren, Hansen Torben, Astrup Arne, Pedersen Oluf, Sørensen Thorkild I A

Abstract excerpt

BACKGROUND: A common single nucleotide polymorphism (SNP) of FTO (rs9939609, T/A) is associated with total body fatness. We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence. METHODOLOGY/PRINCIPAL FINDINGS: Obese young Danish men (n = 753, BMI > or = 31.0 kg/m(2))...

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PMID: 18698412
DOI: 10.1371/journal.pone.0002958
PMCID: PMC2493033

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